Saturday, October 18, 2025

New method smuggles the mRNA through the immune system.


"Scientists armed bacteria with cancer-killing viruses that infiltrate tumors, evade immunity, and attack from within. Credit: Shutterstock" (New Cancer Therapy Smuggles Viruses Past Immune Defenses)


The system can wrap the virus in the protein that is taken from the receiver’s body. 


The biggest problem with cancer medicines and cancer therapies is how to transport medicines into the cancer cells without harming other cells. The most effective therapy is the mRNA therapy, where the mRNA orders the cancer cell to die. The therapy can be based on two ways. The mRNA can simply shut down the energy production or begin the programmed cell death. Or the mRNA can also program the cell organelles to create poisonous proteins that destroy those cells. The problem is that the mRNA is basically an artificial virus. 

And the immune cell can destroy those genomes immediately. The answer to that thing can be the virus that is wrapped in the proteins that are taken from the receiver's own cells. This package allows the virus to travel past the immune system without activating those cells. 

The problem is, how to make enough viruses? And the next thing can be the solution, that is, the game changer in cancer treatment, gene therapies, and many other things. The technology, where viruses are enclosed in bacteria, can revolutionize cancer treatment, but also other genetic engineering solutions can use this kind of technology. 

This new therapy smuggles viruses past immune cells. The idea is that researchers packed viruses in bacteria, which normally use cancer cells as nutrients. Genetically engineered bacteria can also operate in the human body without causing an alert in the immune system. In those bacteria, the system uses genetic engineering to create the DNA that makes the bacteria create antigens that don’t activate the immune system. This type of bacteria, whose shell proteins are similar to the receiver, can operate in many other roles. 

The DNA transfer can make it possible to create bacteria that travel into injuries, and then transform into the tissue cells that the injury needs. The thing is that those genetically engineered cells can make it possible to create new types of gene therapies. And that gives them ultimate possibilities, and those things are also ultimate threats. 

In the wrong hands, this kind of technology makes it possible to create the most feared biological weapons that we can imagine. The ability to create the viruses that cheat certain immune defenses makes it possible to create virus weapons that affect only certain people. The system uses the immune system’s ability, which makes the immune cells attack the organ transplants. 

If those researchers have the DNA of a certain person, they can create the carrier protein that smuggles the virus through the targeted person’s immune system. In that case, other people’s immune system destroys the virus. But the targeted person’s immune system lets the virus, or mRNA, travel through the immune cells. And then those mRNA molecules reprogram targeted cells. 


https://scitechdaily.com/new-cancer-therapy-smuggles-viruses-past-immune-defenses/


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New method smuggles the mRNA through the immune system.

"Scientists armed bacteria with cancer-killing viruses that infiltrate tumors, evade immunity, and attack from within. Credit: Shutters...